CURRENT UNDERSTANDING ON PATHOGENESIS AND EFFECTIVE TREATMENT OF GLYCOGEN STORAGE DISEASE TYPE IB WITH EMPAGLIFLOZIN: NEW INSIGHTS COMING FROM DIABETES FOR ITS POTENTIAL IMPLICATIONS IN OTHER METABOLIC DISORDERS

Glycogen storage type SAFFRON 2020 Ib (GSDIb) is a rare inborn error of metabolism caused by glucose-6-phosphate transporter (G6PT, SLC37A4) deficiency.G6PT defect results in excessive accumulation of glycogen and fat in the liver, kidney, and intestinal mucosa and into both glycogenolysis and gluconeogenesis impairment.Clinical features include he

Find all boils down to is marked with (recruitment aesthetic of digital technology for (color) in the film novelist) And the relationship between the aesthetic employment of digital technology for (color) and its impacts on the level of artistic creativity through digital technology and its impacts on the technical and completed the final film in t

Abstract Background Despite scientific evidence that climate change has profound and far reaching implications for public health, translating this knowledge in a manner that supports citizen engagement, applied decision-making, and behavioural change can be challenging.This is especially true for complex vector-borne zoonotic diseases such as Lyme

Quantum reservoir computing (QRC) has emerged as a promising paradigm for harnessing near-term quantum devices to tackle temporal machine learning tasks.Yet, identifying the mechanisms that underlie enhanced performance remains challenging, particularly in many-body open systems where nonlinear interactions and dissipation intertwine in complex way

Motivated by the dynamics of a trimaran, an investigation of the dynamic behaviour of a double forcing parametrically excited system is carried out.Initially, we provide an outline of Skid Shoes the stability regions, both numerically and analytically, for the undamped linear, extended version of the Mathieu equation.This paper then examines the an